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Identification of Candidate Tumour Suppressor Genes Frequently Methylated in Renal Cell Carcinoma
Promoter region hyermethylation and transcriptional silencing is a frequent cause of tumour suppressor gene (TSG) inactivation in many types of human cancers. Functional epigenetic studies, in which gene expression is induced by treatment with demethylating agents, may identify novel genes with tumo...
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| Hauptverfasser: | , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3021900/ https://ncbi.nlm.nih.gov/pubmed/20154727 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.493 |
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