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Genome-wide CpG island methylation analysis implicates novel genes in the pathogenesis of renal cell carcinoma

In order to identify novel candidate tumor suppressor genes (TSGs) implicated in renal cell carcinoma (RCC), we performed genome-wide methylation profiling of RCC using the HumanMethylation27 BeadChips to assess methylation at >14,000 genes. Two hundred and twenty hypermethylated probes represent...

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Detalhes bibliográficos
Main Authors: Ricketts, Christopher J, Morris, Mark R, Gentle, Dean, Brown, Michael, Wake, Naomi, Woodward, Emma R, Clarke, Noel, Latif, Farida, Maher, Eamonn R
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335951/
https://ncbi.nlm.nih.gov/pubmed/22430804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.7.3.19103
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