Stability of the CpG island methylator phenotype during glioma progression and identification of methylated loci in secondary glioblastomas

BACKGROUND: Grade IV glioblastomas exist in two forms, primary (de novo) glioblastomas (pGBM) that arise without precursor lesions, and the less common secondary glioblastomas (sGBM) which develop from earlier lower grade lesions. Genetic heterogeneity between pGBM and sGBM has been documented as ha...

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Библиографические подробности
Опубликовано в: :BMC Cancer
Главные авторы: Hill, Victoria K, Shinawi, Thoraia, Ricketts, Christopher J, Krex, Dietmar, Schackert, Gabriele, Bauer, Julien, Wei, Wenbin, Cruickshank, Garth, Maher, Eamonn R, Latif, Farida
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2014
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227105/
https://ncbi.nlm.nih.gov/pubmed/25012071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-506
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