Stability of the CpG island methylator phenotype during glioma progression and identification of methylated loci in secondary glioblastomas

BACKGROUND: Grade IV glioblastomas exist in two forms, primary (de novo) glioblastomas (pGBM) that arise without precursor lesions, and the less common secondary glioblastomas (sGBM) which develop from earlier lower grade lesions. Genetic heterogeneity between pGBM and sGBM has been documented as ha...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Hill, Victoria K, Shinawi, Thoraia, Ricketts, Christopher J, Krex, Dietmar, Schackert, Gabriele, Bauer, Julien, Wei, Wenbin, Cruickshank, Garth, Maher, Eamonn R, Latif, Farida
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227105/
https://ncbi.nlm.nih.gov/pubmed/25012071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-506
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