Identification of Candidate Tumour Suppressor Genes Frequently Methylated in Renal Cell Carcinoma

Promoter region hyermethylation and transcriptional silencing is a frequent cause of tumour suppressor gene (TSG) inactivation in many types of human cancers. Functional epigenetic studies, in which gene expression is induced by treatment with demethylating agents, may identify novel genes with tumo...

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Hlavní autoři: Morris, Mark R., Ricketts, Christopher, Gentle, Dean, Abdulrahman, Mahera, Clarke, Noel, Brown, Michael, Kishida, Takeshi, Yao, Masahiro, Latif, Farida, Maher, Eamonn R
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021900/
https://ncbi.nlm.nih.gov/pubmed/20154727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.493
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