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Functional epigenomics approach to identify methylated candidate tumour suppressor genes in renal cell carcinoma

Promoter region hypermethylation and transcriptional silencing is a frequent cause of tumour suppressor gene (TSG) inactivation in many human cancers. Previously, to identify candidate epigenetically inactivated TSGs in renal cell carcinoma (RCC), we monitored changes in gene expression in four RCC...

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Bibliografski detalji
Glavni autori: Morris, M R, Gentle, D, Abdulrahman, M, Clarke, N, Brown, M, Kishida, T, Yao, M, Teh, B T, Latif, F, Maher, E R
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361461/
https://ncbi.nlm.nih.gov/pubmed/18195710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604180
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