Epigenome‐wide analyses identify DNA methylation signatures of dementia risk

INTRODUCTION: Dementia pathogenesis begins years before clinical symptom onset, necessitating the understanding of premorbid risk mechanisms. Here we investigated potential pathogenic mechanisms by assessing DNA methylation associations with dementia risk factors in Alzheimer's disease (AD)–fre...

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Dades bibliogràfiques
Publicat a:Alzheimers Dement (Amst)
Autors principals: Walker, Rosie M., Bermingham, Mairead L., Vaher, Kadi, Morris, Stewart W., Clarke, Toni‐Kim, Bretherick, Andrew D., Zeng, Yanni, Amador, Carmen, Rawlik, Konrad, Pandya, Kalyani, Hayward, Caroline, Campbell, Archie, Porteous, David J., McIntosh, Andrew M., Marioni, Riccardo E., Evans, Kathryn L.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2020
Matèries:
Genetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7416667/
https://ncbi.nlm.nih.gov/pubmed/32789163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12078
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