Epigenome‐wide analyses identify DNA methylation signatures of dementia risk

INTRODUCTION: Dementia pathogenesis begins years before clinical symptom onset, necessitating the understanding of premorbid risk mechanisms. Here we investigated potential pathogenic mechanisms by assessing DNA methylation associations with dementia risk factors in Alzheimer's disease (AD)–fre...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Walker, Rosie M., Bermingham, Mairead L., Vaher, Kadi, Morris, Stewart W., Clarke, Toni‐Kim, Bretherick, Andrew D., Zeng, Yanni, Amador, Carmen, Rawlik, Konrad, Pandya, Kalyani, Hayward, Caroline, Campbell, Archie, Porteous, David J., McIntosh, Andrew M., Marioni, Riccardo E., Evans, Kathryn L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7416667/
https://ncbi.nlm.nih.gov/pubmed/32789163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12078
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