Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD

BACKGROUND: The causes of poor respiratory function and COPD are incompletely understood, but it is clear that genes and the environment play a role. As DNA methylation is under both genetic and environmental control, we hypothesised that investigation of differential methylation associated with the...

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Pubblicato in:EBioMedicine
Autori principali: Bermingham, Mairead L., Walker, Rosie M., Marioni, Riccardo E., Morris, Stewart W., Rawlik, Konrad, Zeng, Yanni, Campbell, Archie, Redmond, Paul, Whalley, Heather C., Adams, Mark J., Hayward, Caroline, Deary, Ian J., Porteous, David J., McIntosh, Andrew M., Evans, Kathryn L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2019
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Research paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557748/
https://ncbi.nlm.nih.gov/pubmed/30935889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.072
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