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Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD

BACKGROUND: The causes of poor respiratory function and COPD are incompletely understood, but it is clear that genes and the environment play a role. As DNA methylation is under both genetic and environmental control, we hypothesised that investigation of differential methylation associated with the...

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Publicado en:EBioMedicine
Main Authors: Bermingham, Mairead L., Walker, Rosie M., Marioni, Riccardo E., Morris, Stewart W., Rawlik, Konrad, Zeng, Yanni, Campbell, Archie, Redmond, Paul, Whalley, Heather C., Adams, Mark J., Hayward, Caroline, Deary, Ian J., Porteous, David J., McIntosh, Andrew M., Evans, Kathryn L.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557748/
https://ncbi.nlm.nih.gov/pubmed/30935889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.03.072
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