Molecular genetic analysis of FIH-1, FH, and SDHB candidate tumour suppressor genes in renal cell carcinoma

Background: Overexpression of the hypoxia inducible factor 1 (HIF-1) and HIF-2 transcription factors and the consequent upregulation of hypoxia inducible mRNAs is a feature of many human cancers and may be unrelated to tissue hypoxia. Thus, the VHL (von Hippel-Lindau) tumour suppressor gene (TSG) re...

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Bibliografische gegevens
Hoofdauteurs: Morris, M R, Maina, E, Morgan, N V, Gentle, D, Astuti, D, Moch, H, Kishida, T, Yao, M, Schraml, P, Richards, F M, Latif, F, Maher, E R
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Copyright 2004 Journal of Clinical Pathology 2004
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Original Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1770369/
https://ncbi.nlm.nih.gov/pubmed/15220362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jcp.2003.011767
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