SLIT2 promoter methylation analysis in neuroblastoma, Wilms' tumour and renal cell carcinoma

The 3p21.3 RASSF1A tumour suppressor gene (TSG) provides a paradigm for TSGs inactivated by promoter methylation rather than somatic mutations. Recently, we identified frequent promoter methylation without somatic mutations of SLIT2 in lung and breast cancers, suggesting similarities between SLIT2 a...

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Hlavní autoři: Astuti, D, da Silva, N F, Dallol, A, Gentle, D, Martinsson, T, Kogner, P, Grundy, R, Kishida, T, Yao, M, Latif, F, Maher, E R
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2004
Témata:
Genetics and Genomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409544/
https://ncbi.nlm.nih.gov/pubmed/14735202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601447
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