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Epigenetic inactivation of SLIT3 and SLIT1 genes in human cancers

In Drosophila, the Slit gene product, a secreted glycoprotein, acts as a midline repellent to guide axonal development during embryogenesis. Three human Slit gene orthologues have been characterised and recently we reported frequent promoter region hypermethylation and transcriptional silencing of S...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dickinson, R E, Dallol, A, Bieche, I, Krex, D, Morton, D, Maher, E R, Latif, F
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409788/
https://ncbi.nlm.nih.gov/pubmed/15534609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602222
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