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Epigenetic inactivation of SLIT3 and SLIT1 genes in human cancers

In Drosophila, the Slit gene product, a secreted glycoprotein, acts as a midline repellent to guide axonal development during embryogenesis. Three human Slit gene orthologues have been characterised and recently we reported frequent promoter region hypermethylation and transcriptional silencing of S...

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Autori principali: Dickinson, R E, Dallol, A, Bieche, I, Krex, D, Morton, D, Maher, E R, Latif, F
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409788/
https://ncbi.nlm.nih.gov/pubmed/15534609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602222
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