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Adverse prognosis of epigenetic inactivation in RUNX3 gene at 1p36 in human pancreatic cancer

Alteration in transforming growth factor-β signalling pathway is one of the main causes of pancreatic cancer. The human runt-related transcription factor 3 gene (RUNX3) is an important component of this pathway. RUNX3 locus 1p36 is commonly deleted in a variety of human cancers, including pancreatic...

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Detalhes bibliográficos
Main Authors: Nomoto, S, Kinoshita, T, Mori, T, Kato, K, Sugimoto, H, Kanazumi, N, Takeda, S, Nakao, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2391125/
https://ncbi.nlm.nih.gov/pubmed/18475302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604333
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