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Adverse prognosis of epigenetic inactivation in RUNX3 gene at 1p36 in human pancreatic cancer
Alteration in transforming growth factor-β signalling pathway is one of the main causes of pancreatic cancer. The human runt-related transcription factor 3 gene (RUNX3) is an important component of this pathway. RUNX3 locus 1p36 is commonly deleted in a variety of human cancers, including pancreatic...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2008
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2391125/ https://ncbi.nlm.nih.gov/pubmed/18475302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604333 |
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