Methylation profiling and evaluation of demethylating therapy in renal cell carcinoma

BACKGROUND: Despite therapeutic advances in targeted therapy, metastatic renal cell carcinoma (RCC) remains incurable for the vast majority of patients. Key molecular events in the pathogenesis of RCC include inactivation of the VHL tumour suppressor gene (TSG), inactivation of chromosome 3p TSGs im...

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Bibliografiska uppgifter
Huvudupphovsmän: Ricketts, Christopher J, Morris, Mark R, Gentle, Dean, Shuib, Salwati, Brown, Michael, Clarke, Noel, Wei, Wenbin, Nathan, Paul, Latif, Farida, Maher, Eamonn R
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2013
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848591/
https://ncbi.nlm.nih.gov/pubmed/24034811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-5-16
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