Methylation profiling and evaluation of demethylating therapy in renal cell carcinoma

BACKGROUND: Despite therapeutic advances in targeted therapy, metastatic renal cell carcinoma (RCC) remains incurable for the vast majority of patients. Key molecular events in the pathogenesis of RCC include inactivation of the VHL tumour suppressor gene (TSG), inactivation of chromosome 3p TSGs im...

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Detalhes bibliográficos
Main Authors: Ricketts, Christopher J, Morris, Mark R, Gentle, Dean, Shuib, Salwati, Brown, Michael, Clarke, Noel, Wei, Wenbin, Nathan, Paul, Latif, Farida, Maher, Eamonn R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3848591/
https://ncbi.nlm.nih.gov/pubmed/24034811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1868-7083-5-16
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