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Inhibition of S-phase progression by adeno-associated virus Rep78 protein is mediated by hypophosphorylated pRb

Adeno-associated virus (AAV) has an antiproliferative action on cells. We investigated the effect of the AAV replication proteins (Rep) on the cell division cycle using retroviral vectors. Rep78 and Rep68 inhibited the growth of primary, immortalized and transformed cells, while Rep52 and Rep40 did...

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Podrobná bibliografie
Vydáno v:EMBO J
Hlavní autoři: Saudan, Philippe, Vlach, Jaromir, Beard, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC302033/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10944118/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.16.4351
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