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Inhibition of S-phase progression by adeno-associated virus Rep78 protein is mediated by hypophosphorylated pRb

Adeno-associated virus (AAV) has an antiproliferative action on cells. We investigated the effect of the AAV replication proteins (Rep) on the cell division cycle using retroviral vectors. Rep78 and Rep68 inhibited the growth of primary, immortalized and transformed cells, while Rep52 and Rep40 did...

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Bibliografische gegevens
Hoofdauteurs: Saudan, Philippe, Vlach, Jaromir, Beard, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2000
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC302033/
https://ncbi.nlm.nih.gov/pubmed/10944118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.16.4351
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