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Inhibition of S-phase progression by adeno-associated virus Rep78 protein is mediated by hypophosphorylated pRb

Adeno-associated virus (AAV) has an antiproliferative action on cells. We investigated the effect of the AAV replication proteins (Rep) on the cell division cycle using retroviral vectors. Rep78 and Rep68 inhibited the growth of primary, immortalized and transformed cells, while Rep52 and Rep40 did...

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書誌詳細
主要な著者: Saudan, Philippe, Vlach, Jaromir, Beard, Peter
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC302033/
https://ncbi.nlm.nih.gov/pubmed/10944118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.16.4351
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