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How adeno-associated virus Rep78 protein arrests cells completely in S phase

Adeno-associated virus Rep78 protein has antiproliferative effects on cells. It inhibits cell cycle progression, and, in particular, Rep78 induces a complete arrest within S phase, a response rarely seen after cell DNA damage. We examined how Rep78 achieves such an efficient S phase block. Rep78 inh...

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Hlavní autoři: Berthet, Carole, Raj, Kenneth, Saudan, Philippe, Beard, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224635/
https://ncbi.nlm.nih.gov/pubmed/16157891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504583102
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