Computationally designed adeno-associated virus (AAV) Rep 78 is efficiently maintained within an adenovirus vector

Adeno-associated virus (AAV) is a single-stranded parvovirus retaining the unique capacity for site-specific integration into a transcriptionally silent region of the human genome, a characteristic requiring the functional properties of the Rep 78/68 polypeptide in conjunction with AAV terminal repe...

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Bibliografische gegevens
Hoofdauteurs: Sitaraman, Varsha, Hearing, Patrick, Ward, Charles B., Gnatenko, Dmitri V., Wimmer, Eckard, Mueller, Steffen, Skiena, Steven, Bahou, Wadie F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2011
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161519/
https://ncbi.nlm.nih.gov/pubmed/21844368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1102883108
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