High-level expression of adeno-associated virus (AAV) Rep78 or Rep68 protein is sufficient for infectious-particle formation by a rep-negative AAV mutant.

Adeno-associated virus (AAV) codes for four closely related nonstructural proteins (Rep) required for AAV DNA replication and gene regulation. In vitro studies have revealed that either Rep78 or Rep68 alone is sufficient for AAV DNA replication. Rep52 and Rep40 are not required for DNA replication b...

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Pubblicato in:	J Virol
Autori principali:	Hölscher, C, Kleinschmidt, J A, Bürkle, A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC189603/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7474103/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.69.11.6880-6885.1995
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