Amino-Terminal Domain Exchange Redirects Origin-Specific Interactions of Adeno-Associated Virus Rep78 In Vitro

The unique ability of adeno-associated virus type 2 (AAV) to site-specifically integrate its genome into a defined sequence on human chromosome 19 (AAVS1) makes it of particular interest for use in targeted gene delivery. The objective underlying this study is to provide evidence for the feasibility...

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Bibliographic Details
Main Authors: Yoon, Miran, Smith, Deborah H., Ward, Peter, Medrano, Francisco J., Aggarwal, Aneel K., Linden, R. Michael
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114116/
https://ncbi.nlm.nih.gov/pubmed/11238849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.7.3230-3239.2001
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