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Adeno-Associated Virus Type 2 Rep78 Inhibition of PKA and PRKX: Fine Mapping and Analysis of Mechanism

Hormones and neurotransmitters utilize cyclic AMP (cAMP) as a second messenger in signal transduction pathways to regulate cell growth and division, differentiation, gene expression, and metabolism. Adeno-associated virus type 2 (AAV-2) nonstructural protein Rep78 inhibits members of the cAMP signal...

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Autors principals: Schmidt, Michael, Chiorini, John A., Afione, Sandra, Kotin, Robert
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC135833/
https://ncbi.nlm.nih.gov/pubmed/11773379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.3.1033-1042.2002
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