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TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain
DNA double-strand breaks enhance homologous recombination in cells and have been exploited for targeted genome editing through use of engineered endonucleases. Here we report the creation and initial characterization of a group of rare-cutting, site-specific DNA nucleases produced by fusion of the r...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3017587/ https://ncbi.nlm.nih.gov/pubmed/20699274 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq704 |
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