TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

DNA double-strand breaks enhance homologous recombination in cells and have been exploited for targeted genome editing through use of engineered endonucleases. Here we report the creation and initial characterization of a group of rare-cutting, site-specific DNA nucleases produced by fusion of the r...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Li, Ting, Huang, Sheng, Jiang, Wen Zhi, Wright, David, Spalding, Martin H., Weeks, Donald P., Yang, Bing
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2011
Schlagworte:
Synthetic Biology and Chemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017587/
https://ncbi.nlm.nih.gov/pubmed/20699274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq704
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge