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Structure of FokI has implications for DNA cleavage

FokI is a member an unusual class of restriction enzymes that recognize a specific DNA sequence and cleave nonspecifically a short distance away from that sequence. FokI consists of an N-terminal DNA recognition domain and a C-terminal cleavage domain. The bipartite nature of FokI has led to the dev...

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Detalles Bibliográficos
Main Authors: Wah, David A., Bitinaite, Jurate, Schildkraut, Ira, Aggarwal, Aneel K.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC27934/
https://ncbi.nlm.nih.gov/pubmed/9724743
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