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Structure of FokI has implications for DNA cleavage

FokI is a member an unusual class of restriction enzymes that recognize a specific DNA sequence and cleave nonspecifically a short distance away from that sequence. FokI consists of an N-terminal DNA recognition domain and a C-terminal cleavage domain. The bipartite nature of FokI has led to the dev...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Wah, David A., Bitinaite, Jurate, Schildkraut, Ira, Aggarwal, Aneel K.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27934/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9724743/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.18.10564
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