FokI dimerization is required for DNA cleavage

FokI is a type IIs restriction endonuclease comprised of a DNA recognition domain and a catalytic domain. The structural similarity of the FokI catalytic domain to the type II restriction endonuclease BamHI monomer suggested that the FokI catalytic domains may dimerize. In addition, the FokI structu...

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Bibliografske podrobnosti
Main Authors: Bitinaite, Jurate, Wah, David A., Aggarwal, Aneel K., Schildkraut, Ira
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1998
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC27935/
https://ncbi.nlm.nih.gov/pubmed/9724744
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