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Modularly assembled designer TAL effector nucleases for targeted gene knockout and gene replacement in eukaryotes
Recent studies indicate that the DNA recognition domain of transcription activator-like (TAL) effectors can be combined with the nuclease domain of FokI restriction enzyme to produce TAL effector nucleases (TALENs) that, in pairs, bind adjacent DNA target sites and produce double-strand breaks betwe...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3152341/ https://ncbi.nlm.nih.gov/pubmed/21459844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr188 |
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