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Novel analogues of the therapeutic complement inhibitor compstatin with significantly improved affinity and potency(1)
Compstatin is a 13-residue disulfide-bridged peptide that inhibits a key step in the activation of the human complement system. Compstatin and its derivatives have shown great promise for the treatment of many clinical disorders associated with unbalanced complement activity. To obtain more potent c...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3014449/ https://ncbi.nlm.nih.gov/pubmed/21067811 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2010.10.004 |
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