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Assessing siRNA Pharmacodynamics in a Luciferase-expressing Mouse
A significant barrier to the successful general development of small-interfering RNA (siRNA) therapeutics is the ability to deliver them systemically to target organs and cell types. In this study, we have developed a mouse strain that will facilitate the evaluation of the efficacy of siRNA delivery...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3014086/ https://ncbi.nlm.nih.gov/pubmed/18781145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.187 |
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