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Epigenetic Histone Methylation Modulates Fibrotic Gene Expression
TGF-β1–induced expression of extracellular matrix (ECM) genes plays a major role in the development of chronic renal diseases such as diabetic nephropathy. Although many key transcription factors are known, mechanisms involving the nuclear chromatin that modulate ECM gene expression remain unclear....
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society of Nephrology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3014020/ https://ncbi.nlm.nih.gov/pubmed/20930066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010060633 |
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