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Epigenetic Histone Methylation Modulates Fibrotic Gene Expression

TGF-β1–induced expression of extracellular matrix (ECM) genes plays a major role in the development of chronic renal diseases such as diabetic nephropathy. Although many key transcription factors are known, mechanisms involving the nuclear chromatin that modulate ECM gene expression remain unclear....

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Bibliografiske detaljer
Main Authors: Sun, Guangdong, Reddy, Marpadga A., Yuan, Hang, Lanting, Linda, Kato, Mitsuo, Natarajan, Rama
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014020/
https://ncbi.nlm.nih.gov/pubmed/20930066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010060633
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