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Epigenetic Histone Methylation Modulates Fibrotic Gene Expression

TGF-β1–induced expression of extracellular matrix (ECM) genes plays a major role in the development of chronic renal diseases such as diabetic nephropathy. Although many key transcription factors are known, mechanisms involving the nuclear chromatin that modulate ECM gene expression remain unclear....

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Detalhes bibliográficos
Main Authors: Sun, Guangdong, Reddy, Marpadga A., Yuan, Hang, Lanting, Linda, Kato, Mitsuo, Natarajan, Rama
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3014020/
https://ncbi.nlm.nih.gov/pubmed/20930066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2010060633
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