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Inhibiting MicroRNA-192 Ameliorates Renal Fibrosis in Diabetic Nephropathy
TGF-β1 upregulates microRNA-192 (miR-192) in cultured glomerular mesangial cells and in glomeruli from diabetic mice. miR-192 not only increases collagen expression by targeting the E-box repressors Zeb1/2 but also modulates other renal miRNAs, suggesting that it may be a therapeutic target for diab...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Nephrology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3294315/ https://ncbi.nlm.nih.gov/pubmed/22223877 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011050485 |
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