Transforming Growth Factor-β–Induced Cross Talk Between p53 and a MicroRNA in the Pathogenesis of Diabetic Nephropathy

Elevated p53 expression is associated with several kidney diseases including diabetic nephropathy (DN). However, the mechanisms are unclear. We report that expression levels of transforming growth factor-β1 (TGF-β), p53, and microRNA-192 (miR-192) are increased in the renal cortex of diabetic mice,...

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Главные авторы: Deshpande, Supriya D., Putta, Sumanth, Wang, Mei, Lai, Jennifer Y., Bitzer, Markus, Nelson, Robert G., Lanting, Linda L., Kato, Mitsuo, Natarajan, Rama
Формат: Artigo
Язык:Inglês
Опубликовано: American Diabetes Association 2013
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Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749352/
https://ncbi.nlm.nih.gov/pubmed/23649518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0305
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