Transforming Growth Factor-β–Induced Cross Talk Between p53 and a MicroRNA in the Pathogenesis of Diabetic Nephropathy

Elevated p53 expression is associated with several kidney diseases including diabetic nephropathy (DN). However, the mechanisms are unclear. We report that expression levels of transforming growth factor-β1 (TGF-β), p53, and microRNA-192 (miR-192) are increased in the renal cortex of diabetic mice,...

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Detaylı Bibliyografya
Asıl Yazarlar: Deshpande, Supriya D., Putta, Sumanth, Wang, Mei, Lai, Jennifer Y., Bitzer, Markus, Nelson, Robert G., Lanting, Linda L., Kato, Mitsuo, Natarajan, Rama
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Diabetes Association 2013
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749352/
https://ncbi.nlm.nih.gov/pubmed/23649518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0305
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