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Reduced Autophagy by a microRNA-mediated Signaling Cascade in Diabetes-induced Renal Glomerular Hypertrophy

Autophagy plays a key role in the pathogenesis of kidney diseases, however its role in diabetic nephropathy (DN), and particularly in kidney glomerular mesangial cells (MCs) is not very clear. Transforming Growth Factor- β1 (TGF-β), a key player in the pathogenesis of DN, regulates expression of var...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Deshpande, Supriya, Abdollahi, Maryam, Wang, Mei, Lanting, Linda, Kato, Mitsuo, Natarajan, Rama
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934412/
https://ncbi.nlm.nih.gov/pubmed/29725042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25295-x
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