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Epigenetic histone H3 lysine 9 methylation in metabolic memory and inflammatory phenotype of vascular smooth muscle cells in diabetes

Diabetic patients continue to develop inflammation and vascular complications even after achieving glycemic control. This poorly understood “metabolic memory” phenomenon poses major challenges in treating diabetes. Recent studies demonstrate a link between epigenetic changes such as chromatin histon...

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Detalhes bibliográficos
Main Authors: Villeneuve, Louisa M., Reddy, Marpadga A., Lanting, Linda L., Wang, Mei, Meng, Li, Natarajan, Rama
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2449362/
https://ncbi.nlm.nih.gov/pubmed/18579779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803623105
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