Enhanced Levels of microRNA-125b in Vascular Smooth Muscle Cells of Diabetic db/db Mice Lead to Increased Inflammatory Gene Expression by Targeting the Histone Methyltransferase Suv39h1

OBJECTIVE: Diabetes remains a major risk factor for vascular complications that seem to persist even after achieving glycemic control, possibly due to “metabolic memory.” Using cultured vascular smooth muscle cells (MVSMC) from type 2 diabetic db/db mice, we recently showed that decreased promoter o...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Villeneuve, Louisa M., Kato, Mitsuo, Reddy, Marpadga A., Wang, Mei, Lanting, Linda, Natarajan, Rama
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Diabetes Association 2010
Gaiak:
Complications
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2963550/
https://ncbi.nlm.nih.gov/pubmed/20699419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0208
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