Epigenetic Histone Modifications Involved in Profibrotic Gene Regulation by 12/15-Lipoxygenase and Its Oxidized Lipid Products in Diabetic Nephropathy

Aims: Epigenetic mechanisms, including histone post-translational modifications and DNA methylation, are implicated in the pathogenesis of diabetic nephropathy (DN), but the mediators are not well known. Moreover, although dyslipidemia contributes to DN, epigenetic changes triggered by lipids are un...

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Detalhes bibliográficos
Publicado no:Antioxid Redox Signal
Main Authors: Yuan, Hang, Reddy, Marpadga A., Deshpande, Supriya, Jia, Ye, Park, Jung Tak, Lanting, Linda L., Jin, Wen, Kato, Mitsuo, Xu, Zhong Gao, Das, Sadhan, Natarajan, Rama
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2016
Assuntos:
Original Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779982/
https://ncbi.nlm.nih.gov/pubmed/26492974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2015.6372
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