Epigenetic Histone Modifications Involved in Profibrotic Gene Regulation by 12/15-Lipoxygenase and Its Oxidized Lipid Products in Diabetic Nephropathy

Aims: Epigenetic mechanisms, including histone post-translational modifications and DNA methylation, are implicated in the pathogenesis of diabetic nephropathy (DN), but the mediators are not well known. Moreover, although dyslipidemia contributes to DN, epigenetic changes triggered by lipids are un...

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Vydáno v:Antioxid Redox Signal
Hlavní autoři: Yuan, Hang, Reddy, Marpadga A., Deshpande, Supriya, Jia, Ye, Park, Jung Tak, Lanting, Linda L., Jin, Wen, Kato, Mitsuo, Xu, Zhong Gao, Das, Sadhan, Natarajan, Rama
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2016
Témata:
Original Research Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779982/
https://ncbi.nlm.nih.gov/pubmed/26492974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2015.6372
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