Epigenetic Histone Modifications Involved in Profibrotic Gene Regulation by 12/15-Lipoxygenase and Its Oxidized Lipid Products in Diabetic Nephropathy

Aims: Epigenetic mechanisms, including histone post-translational modifications and DNA methylation, are implicated in the pathogenesis of diabetic nephropathy (DN), but the mediators are not well known. Moreover, although dyslipidemia contributes to DN, epigenetic changes triggered by lipids are un...

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Veröffentlicht in:Antioxid Redox Signal
Hauptverfasser: Yuan, Hang, Reddy, Marpadga A., Deshpande, Supriya, Jia, Ye, Park, Jung Tak, Lanting, Linda L., Jin, Wen, Kato, Mitsuo, Xu, Zhong Gao, Das, Sadhan, Natarajan, Rama
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2016
Schlagworte:
Original Research Communications
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779982/
https://ncbi.nlm.nih.gov/pubmed/26492974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2015.6372
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