Epigenetic Histone Modifications Involved in Profibrotic Gene Regulation by 12/15-Lipoxygenase and Its Oxidized Lipid Products in Diabetic Nephropathy

Aims: Epigenetic mechanisms, including histone post-translational modifications and DNA methylation, are implicated in the pathogenesis of diabetic nephropathy (DN), but the mediators are not well known. Moreover, although dyslipidemia contributes to DN, epigenetic changes triggered by lipids are un...

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Dettagli Bibliografici
Pubblicato in:Antioxid Redox Signal
Autori principali: Yuan, Hang, Reddy, Marpadga A., Deshpande, Supriya, Jia, Ye, Park, Jung Tak, Lanting, Linda L., Jin, Wen, Kato, Mitsuo, Xu, Zhong Gao, Das, Sadhan, Natarajan, Rama
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2016
Soggetti:
Original Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779982/
https://ncbi.nlm.nih.gov/pubmed/26492974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2015.6372
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