High Potassium Intake Enhances the Inhibitory Effect of 11,12-EET on ENaC

High dietary potassium stimulates the renal expression of cytochrome P450 (CYP) epoxygenase 2C23, which metabolizes arachidonic acid (AA). Because the AA metabolite 11,12-epoxyeicosatrienoic acid (11,12-EET) can inhibit the epithelial sodium channel (ENaC) in the cortical collecting duct, we tested...

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Autors principals: Sun, Peng, Lin, Dao-Hong, Yue, Peng, Jiang, Houli, Gotlinger, Katherine H., Schwartzman, Michal L., Falck, John R., Goli, Mohan, Wang, Wen-Hui
Format: Artigo
Idioma:Inglês
Publicat: American Society of Nephrology 2010
Matèries:
Basic Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3013540/
https://ncbi.nlm.nih.gov/pubmed/20595684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2009111110
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