Mice heterozygous for β-ENaC deletion have defective potassium excretion

The present studies were designed to determine whether mice heterozygous for deletion of β-ENaC exhibited defects in Na(+)/K(+) transport and blood pressure regulation. In response to an acute KCl infusion, +/− mice developed higher serum [K(+)] and excreted only 40% of the K(+) excreted by +/+ mice...

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Main Authors: Cao, X. Renee, Shi, P. Peter, Sigmund, Rita D., Husted, Russell F., Sigmund, Curt D., Williamson, Roger A., Stokes, John B., Yang, Baoli
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818793/
https://ncbi.nlm.nih.gov/pubmed/16571596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00159.2005
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