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11,12-EET increases porto-sinusoidal resistance and may play a role in endothelial dysfunction of portal hypertension
CYP450-dependent epoxyeicosatrienoic acids (EETs) are potent arterial vasodilators, while 20-hydroxyeicosatatraenoic acid (20-HETE) is a vasoconstrictor. We evaluated their role in the control of portal circulation in normal and cirrhotic (CCl(4) induced) isolated perfused rat liver. Phenylephrine (...
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| Publicado en: | Prostaglandins Other Lipid Mediat |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4540347/ https://ncbi.nlm.nih.gov/pubmed/21856435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2011.08.002 |
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