11,12-EET increases porto-sinusoidal resistance and may play a role in endothelial dysfunction of portal hypertension

CYP450-dependent epoxyeicosatrienoic acids (EETs) are potent arterial vasodilators, while 20-hydroxyeicosatatraenoic acid (20-HETE) is a vasoconstrictor. We evaluated their role in the control of portal circulation in normal and cirrhotic (CCl(4) induced) isolated perfused rat liver. Phenylephrine (...

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Detaylı Bibliyografya
Yayımlandı:Prostaglandins Other Lipid Mediat
Asıl Yazarlar: Sacerdoti, David, Jiang, Houli, Gaiani, Silvia, McGiff, John C., Gatta, Angelo, Bolognesi, Massimo
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540347/
https://ncbi.nlm.nih.gov/pubmed/21856435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.prostaglandins.2011.08.002
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