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Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

Damage to mitochondria can lead to the depolarization of the inner mitochondrial membrane, thereby sensitizing impaired mitochondria for selective elimination by autophagy. However, fusion of uncoupled mitochondria with polarized mitochondria can compensate for damage, reverse membrane depolarizatio...

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Bibliografski detalji
Glavni autori: Tanaka, Atsushi, Cleland, Megan M., Xu, Shan, Narendra, Derek P., Suen, Der-Fen, Karbowski, Mariusz, Youle, Richard J.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010068/
https://ncbi.nlm.nih.gov/pubmed/21173115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201007013
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