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Regulating Mitochondrial Outer Membrane Proteins by Ubiquitination and Proteasomal Degradation

Mitochondrial outer membrane proteins have been found to be ubiquitinated and degraded by the proteasome. This process shares at least one component of the ERAD pathway of ER membrane protein degradation, the AAA ATPase cdc48/p97/VCP, thought to extract integral membrane proteins from the lipid bila...

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Autors principals: Karbowski, Mariusz, Youle, Richard J.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155757/
https://ncbi.nlm.nih.gov/pubmed/21705204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2011.05.007
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