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Regulation of FoxO protein stability via ubiquitination and proteasome degradation

Forkhead box O-class (FOXO) proteins are evolutionally conserved transcription factors. They belong to a family of proteins consisting of FOXO1, FOXO3a, FOXO4 and FOXO6 in humans. Increasing evidence suggests that FOXO proteins function as tumor suppressors by transcriptionally regulating expression...

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Bibliografische gegevens
Hoofdauteurs: Huang, Haojie, Tindall, Donald J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3110514/
https://ncbi.nlm.nih.gov/pubmed/21238503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2011.01.007
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