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Regulation of FoxO protein stability via ubiquitination and proteasome degradation
Forkhead box O-class (FOXO) proteins are evolutionally conserved transcription factors. They belong to a family of proteins consisting of FOXO1, FOXO3a, FOXO4 and FOXO6 in humans. Increasing evidence suggests that FOXO proteins function as tumor suppressors by transcriptionally regulating expression...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3110514/ https://ncbi.nlm.nih.gov/pubmed/21238503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2011.01.007 |
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