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Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy
Stresses like low nutrients, systemic inflammation, cancer or infections provoke a catabolic state characterized by enhanced muscle proteolysis and amino acid release to sustain liver gluconeogenesis and tissue protein synthesis. These conditions activate the family of Forkhead Box (Fox) O transcrip...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Pub. Group
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4403316/ https://ncbi.nlm.nih.gov/pubmed/25858807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7670 |
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