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Parkin and Mitofusins Reciprocally Regulate Mitophagy and Mitochondrial Spheroid Formation
Mitochondrial homeostasis via mitochondrial dynamics and quality control is crucial to normal cellular functions. Mitophagy (mitochondria removed by autophagy) stimulated by a mitochondrial uncoupler, carbonyl cyanide m-chlorophenylhydrazone (CCCP), requires Parkin, but it is not clear why Parkin is...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3516781/ https://ncbi.nlm.nih.gov/pubmed/23095748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.413682 |
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