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Parkin and Mitofusins Reciprocally Regulate Mitophagy and Mitochondrial Spheroid Formation
Mitochondrial homeostasis via mitochondrial dynamics and quality control is crucial to normal cellular functions. Mitophagy (mitochondria removed by autophagy) stimulated by a mitochondrial uncoupler, carbonyl cyanide m-chlorophenylhydrazone (CCCP), requires Parkin, but it is not clear why Parkin is...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3516781/ https://ncbi.nlm.nih.gov/pubmed/23095748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.413682 |
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