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Role of Fibrinogen and Protease-Activated Receptors in Acute Xenobiotic-Induced Cholestatic Liver Injury
Alpha-naphthylisothiocyanate (ANIT)–induced cholestatic liver injury causes tissue factor (TF)–dependent coagulation in mice, and TF deficiency reduces ANIT-induced liver injury. However, the mechanism whereby TF contributes to hepatotoxicity in this model is not known. Utilizing pharmacological and...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2011
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003835/ https://ncbi.nlm.nih.gov/pubmed/20974703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq327 |
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